Mania induced by varenicline
نویسندگان
چکیده
Varenicline is sometimes used in the treatment of smoking addiction. Side effects such as nausea, vomiting, and headaches have been well documented. In addition, depressed mood and suicidal thoughts relating to varenicline usage have been previously reported. We report a case of mania in a patient with refractory depression whose first manic episode developed under the use of varenicline in combination with original antidepressant medications. Cheng-Ta Li ( ) Corresponding author: [email protected] Chang PT and Li CT. How to cite this article: Mania induced by varenicline [version 1; referees: 1 approved with reservations, 1 not 2013, :183 (doi: ) approved] F1000Research 2 10.12688/f1000research.2-183.v1 © 2013 Chang PT and Li CT. This is an open access article distributed under the terms of the , Copyright: Creative Commons Attribution Licence which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Data associated with the article are available under the terms of the (CC0 1.0 Public domain dedication). Creative Commons Zero "No rights reserved" data waiver The author(s) declared that no grants were involved in supporting this work. Grant information: Competing interests: No competing interests were disclosed. 13 Sep 2013, :183 (doi: ) First published: 2 10.12688/f1000research.2-183.v1 Referee Status:
منابع مشابه
Late-life Onset Mania After Varenicline Use: A Case Report.
Late-life onset manic attacks generally occur secondary to general medical conditions or drug use. Varenicline is an α4β2 nicotinic acetylcholine receptor partial agonist, used for the cessation of smoking. In this case report, we present a 67-year-old male patient with a new-onset manic episode following varenicline treatment. The patient's manic symptoms started on the seventh day of varenicl...
متن کاملVarenicline Ameliorates Learning and Memory Deficits in Amyloid β(25–35) Rat Model of Alzheimer’s Disease
Introduction: Alzheimer’s disease (AD) is a enfeeble neurodegenerative disorder characterized by increased β-amyloid (Aβ) deposition and neuronal dysfunction leading to impaired learning and recall. Among proposed risk factors, impaired cholinergic transmission is a main cause for incidence of disease. Methods: In the present study, effects of the intracerebroventricularly administration of an ...
متن کاملDrug-induced liver injury due to varenicline: a case report
BACKGROUND Liver injury due to prescription and nonprescription medications is an expanding public health concern in the United States, with drug-induced liver injury (DILI) being the single most common reason for regulatory actions instituted by the Food and Drug Administration against certain medications and supplements. CASE PRESENTATION A 69-year-old Latino man was referred to Hepatology ...
متن کاملEvaluation of reproductive and renal toxicity of varenicline in male rats
Objective(s): Varenicline is a selective partial agonist for the nicotinic acetylcholine receptor a4b2 subtype, which is widely used to treat smoking addiction. However, there is still no data about its potential toxic effects on tissues. In this study, we aimed to determine the varenicline-induced toxicity on reproductive and renal tissues in rats.Ma...
متن کامل